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The active forms of vitamin B12, methylcobalamin, and folate/folic acid, L-methylfolate, help in maintaining normal plasma levels of the protein metabolite homocysteine.
Homocysteine can be re-methylated back to methionine via donation of a methyl group from L-methylfolate, with methylcobalamin acting as a necessary cofactor in this remethylation process.
This formula can be indicated for individuals with MTHFR genetic mutations, as well as elevated homocysteine levels.
